This page contains IGN's Walkthrough for Blood Simple, the tenth main quest of The Witcher 3's first DLC expansion, Blood and Wine.

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To the Orphanage

After you decide to go with Orianna in The Night of Long Fangs, the game will jump you to the orphanage where a massacre has taken place. Orianna stays with remaining survivor as you go looking for clues in the area.

Use your Witcher Senses to look around to find dead bodies inside and outside, along with some claw marks on the outside of the building and some beast paw prints. The most important thing to investigate is at the bottom of the stairs leading to the orphanage. On the small wall of the stairs you'll find the scent of the beast.

Follow the scent over the wall and to another victim. This one has venom left on him that you'll need to examine. After that, hop into the stable and examine the missing cart. And finally use your Witcher Senses to see the tracks of the missing cart.

Hop on Roach and follow the tracks into the creek and finally to the bank of the river. From here, find the Alpha Garkain hanging from below the bridge.

Fighting the Alpha

This fight with the Alpha Garkain is similar to fights you've had before with other vampire creatures. His main attack that you'll need to watch out for is sonic wave that you can see coming as it needs time to charge it up. Keep your distance or attack before it has the chance to use the attack.

Other things to note include making sure you use your Vampire Oil along with having Black Blood potions available when needed. Moon Dust bombs and Samum bombs are also effective here.

Return to the orphanage to find Orianna suckin' up some blood from the child who survived the massacre. After a short lived stand off, Geralt vows to return to end Orianna, but after he's dealt with the bigger problems at hand.

From here, leave the orphanage and walk over to the nearby tree across the dirt road. Speak to the ravens. You'll have the choice to either run over to Regis yourself or warp to him immediately.

In your conversation with Regis, you'll have the option to return to the previous path and search for Syanna to get to Beyond Hill and Dale, or continue on through this path to get to What Lies Unseen.